报告题目

Using Light to Make (Bio)Materials Smart

报告人

邵柏豪 助理教授

报告人单位

香港中文大学

报告时间

2025年10月13日（星期一）14:00

报告地点

近代物理楼509会议室

主办单位

精准智能化学全国重点实验室

报告摘要

Controlled and targeted delivery of therapeutics aids the global efforts towards managing further aggravation of escalating incidence and mortality of many leading diseases as well as improving the quality of life for people suffering from chronic diseases. Photoresponsive therapeutics promise a highly programmable and point-of-care therapeutic modality with spatiotemporal control of light. This prospect, however, has yet to be fully harvested largely owing to insufficient in vivo delivery of light and yet-to-be-optimized ADME properties, i.e., absorption, distribution, metabolism and excretion, of the light-activated systems. To address these limitations, we attempt to survey these challenges from a bioengineering perspective and propose interdisciplinary approaches to enable the light-activated molecules and materials to better meet the needs and criteria for clinical applications. In this seminar, the presenter will cover his doctorate work in the development of hydrazone-based photoswitches and focus on his postdoctoral projects around the concept of bioengineering phototherapeutics.  

报告人简介

邵柏豪博士于2025年8月加入香港中文大学生物医学工程学系，任校长特聘助理教授。课题组聚焦于光响应材料、药物递送、有机和超分子化学的研究。2015年本科毕业于浙江大学药学院（导师：李新和胡永洲教授），2021年博士毕业于美国达特茅斯学院化学系（导师：Prof. Ivan Aprahamian）。2022至2025年间，先后在英国帝国理工学院材料和生物工程学系和牛津大学Kavli纳米科学研究所完成博士后训练（导师：Prof. Dame Molly Stevens）。目前已在Science、JACS、Chem、Angewandte等期刊发表20余篇论文。先后获得过港中文校长青年教授计划（2025）、美国前瞻学会纳米科技奖学金（2024）、欧盟玛丽居里奖学金（2022）、国家优秀自费留学生奖学金（2021）、The Hannah T. Croasdale Graduate Scholar Award（2021）和The Arthur Dunham Holmes 1906 Memorial Graduate Fellowship（2019）等奖项或荣誉。