姓名:邓正玉
职称:特任教授
单位:中国科学技术大学
邮箱:zydeng@ustc.edu.cn
主要研究方向与成果：
主要从事触发式解聚高分子材料设计合成以及药物递送屏障机制研究，解决功能材料和生物医学领域的挑战。i) 创制具有精准结构的触发式解聚高分子和主链可精准编辑的高分子材料，应用于先进制造与生物医药；ii) 开发选择性蛋白质降解与清除材料，主动调控与克服药物递送屏障。已在J. Am. Chem. Soc., Angew. Chem. Int. Ed., Prog. Polym. Sci., JACS Au等国际国内学术期刊上发表SCI论文40余篇。
1. Wenjin Li,# Mingxuan Hou,# Minglong Chen,#; Zhihua He, Jialin Zhang, Jie Cen,* Jinming Hu,* Jiajia Tan,* Zhengyu Deng,* and Shiyong Liu,* Photoresponsive Discoidal Polymersomes With Tracelessly Crosslinkable Bilayers for Intracellular Drug Delivery, Angew. Chem. Int. Ed. 2026, 65, e9958935.
2. Mingxuan Hou,# Wenjin Li,# Jie Cen,# Wenhao Pan,* Zhengyu Deng,* Jinming Hu,* and Shiyong Liu,* Insight into Lysine Selection via Controlled Degradation of 2,4‐Diaminobutyric Acid and Ornithine Polypeptides, Angew. Chem. Int. Ed. 2025, 64, e202502629.
3. Zhengyu Deng, and Elizabeth R. Gillies,* Self-Immolative Polymers Derived from Renewable Resources via Thiol−Ene Chemistry, Angew. Chem. Int. Ed. 2025, 64, e202420054.
4. Jie Cen,# Wen Liu,# Jie Xu,# Xiuxia Wang, Jialin Zhang, Jin Zhang, Zhengyu Deng,* Chenggang Zhou,* Jinming Hu,* and Shiyong Liu,* Single‐Component High‐Resolution Dual‐Tone EUV Photoresists Based on Precision Self‐Immolative Polymers, Angew. Chem. Int. Ed. 2025, 64, e202415588.
5. Zhengyu Deng, Xiaoli Liang, and Elizabeth R. Gillies,* Click to Self-immolation: A “Click” Functionalization Strategy towards Triggerable Self-Immolative Homopolymers and Block Copolymers, Angew. Chem. Int. Ed. 2024, 63, e202317063.