姓名:刘扬中
职称:教授
单位:中国科学技术大学
邮箱:liuyz@ustc.edu.cn
从事金属化学生物学研究，聚焦金属蛋白与金属药物的作用机制，并致力于开发精准靶向肿瘤细胞的纳米抗体药物偶联物。同时，探究金属离子在神经退行性疾病相关蛋白质中的功能及其干预策略。
1. Wenxin Yu,# Duo Jin,# Yajie Zhang, Shenghu Wang, Jiaji Yu, Manman Liu, Yi Dai, Yichen Yin, Junjie Cheng*, Yangzhong Liu*. Provoking tumor disulfidptosis by single-atom nanozyme via regulating cellular energy supply and reducing power. Nat. Commun., 2025, 16, 4877
2. Manman Liu, Duo Jin, Wenxin Yu, Jiaji Yu, Kaiming Cao, Junjie Cheng, Xiaohu Zheng, Andrew Wang, Yangzhong Liu*. Enhancing Tumor Immunotherapy by Multivalent anti-PD-L1 Nanobody Assembled via Ferritin Nanocage. Advanced Science 2024, 11(20), 202308248
3. Junjie Cheng#*, Li Li#, Duo Jin#, Yajie Zhang, Wenxin Yu, Jiaji Yu, Jianhua Zou, Yi Dai, Yang Zhu, Manman Liu, Miya Zhang, Yongfu Sun*, Yangzhong Liu*, Xiaoyuan Chen*. A non-metal single atom nanozyme for cutting off the energy and reducing the power of tumors. Angew. Chem. Int. Ed. , 2024, 63(16), e202319982
4. Yu Wang,# Kaiming Cao,# Mingxi Zong, Siming Yuan, Na Zhang,Yangzhong Liu*. Mutual promotion of co-condensation of KRAS G-quadruplex and a well-folded protein HMGB1. Nucleic Acids Res. , 2024, 52(1), 288–299
5. Kaiming Cao,# Yang Zhu,# Manman Liu, Yanyan Yang, Hongze Hu, Yi Dai, Yu Wang, Siming Yuan, Jiaming Mei,* Peter J. Sadler,* Yangzhong Liu*. -Synuclein as a Target for Metallo-Anti-Neurodegenerative Angew. Chem. Int. Ed. , 2023, 62(1), e202215360
6. Junjie Cheng,# * Yang Zhu,# Yi Dai,# Li Li, Miya Zhang, Duo Jin, Manman Liu, Jiaji Yu, Wenxin Yu, Dan Su, Jianhua Zou,* Xiaoyuan Chen,* Yangzhong Liu*. Gas-Mediated Tumor Energy Remodeling for Sensitizing Mild Photothermal Therapy. Angew. Chem. Int. Ed., 2023, 62(27), e202304312
7. Junjie Cheng,# * Li Li,# Duo Jin,# Yi Dai, Yang Zhu, Jianhua Zou, Manman Liu, Wenxin Yu, Jiaji Yu, Yongfu Sun*, Xiaoyuan Chen,* Yangzhong Liu*. Boosting Ferroptotic Therapy with Iridium Single Atom Nanocatalyst in Ultra-low Metal Content. Adv. Mater. 2023, 35(17), 202210037
5. Siming Yuan, Yang Zhu, Yi Dai, Yu Wang, Duo Jin, Manman Liu, Liqin Tang,* Fabio Arnesano, Giovanni Natile,* Yangzhong Liu*. 19F NMR Allows to Investigate the Fate of Platinum(IV) Prodrugs in Physiological Conditions, Angew. Chem. Int. Ed., 2022, 61(4) e202114250
5. Yang Zhu,# Wenyu Wang,# Junjie Cheng,# Chao Zhao, Yi Dai, Manman Liu, Jianing Yu, Chengming Wang, Huijuan Wang, Sicong Wang, Yunteng Qu, Yuen Wu*, Yangzhong Liu*. Stimuli-Responsive Manganese Single-Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactions, Angew. Chem. Int. Ed., 2021, 60(17), 9480-9488