姓名:张清伟 特任研究员 单位:中国科学技术大学 邮箱:qingweiz@ustc.edu.cn |
主要研究方向与成果:
主要研究方向为络合性元素手性合成。通过机理研究实现了氢膦(酰基)化反应区域与对映选择性的精准控制,开发了零价与二价镍的两种不同催化模式促进的系列反应。
代表性论文:
[1] Wei-Han Wang; Yue Wu; Hai-Tao Wang; Peng-Jia Qi; Wen-Ning Lan; Qing-Wei Zhang*, Enantioselective synthesis of P-stereogenic allenylphosphines through Ni-catalysed propargylic substitution, Nat. Synth., 2022, 1, 738.
[2] Liu, Xu-Teng; Han, Xue-Yu; Wu, Yue; Sun, Ying-Ying; Gao, Li; Huang, Zhuo; Zhang, Qing-Wei*, Ni-Catalyzed Asymmetric Hydrophosphination of Unactivated Alkynes,J. Am. Chem. Soc. 2021, 143, 11309.
[3] Xu-Teng Liu; Ya-Qian Zhang; Xue-Yu Han; Shi-Ping Sun; Qing-Wei Zhang*, Ni-Catalyzed Asymmetric Allylation of Secondary Phosphine Oxides, J. Am. Chem. Soc. 2019, 141, 16584.
[4] Ya-Qian Zhang; Xue-Yu Han; Yue Wu; Peng-Jia Qi; Qing Zhang; Qing-Wei Zhang*, Ni-Catalyzed Asymmetric Hydrophosphinylation of Conjugated Enynes and Mechanistic Studies, Chem. Sci., 2022, 13, 4095-4102.
[5] An, Kun; Ma, Wenpeng; Liu, Li-Chuan; He, Tao; Guan, Guiyu; Zhang, Qing-Wei*; He, Wei*, Rhodium hydride enabled enantioselective intermolecular C–H silylation to access acyclic stereogenic Si–H, Nat. Commun., 2022, 13, 847.