刘扬中

发布者：冯硕发布时间：2023-07-25动态浏览次数：11



姓名：刘扬中 教授


单位：中国科学技术大学


邮箱：liuyz@ustc.edu.cn


主要研究方向与成果：

从事金属化学生物学方向研究，发现铂类药物与铜转运蛋白的反应在药物摄取与外排中的作用机制；设计精准靶向肿瘤细胞的纳米抗体药物偶联物。


代表性论文：

  1. Junjie Cheng,#* Li Li,# Duo Jin,# Yi Dai, Yang Zhu, Jianhua Zou, Manman Liu, Wenxin Yu, Jiaji Yu, Yongfu Sun*, Xiaoyuan Chen,* Yangzhong Liu*. Boosting Ferroptotic Therapy with Iridium Single Atom Nanocatalyst in Ultra-low Metal Content. Adv. Mater. 2023, doi:10.1002/adma.202210037

  2. Kaiming Cao,# Yang Zhu,# Manman Liu, Yanyan Yang, Hongze Hu, Yi Dai, Yu Wang, Siming Yuan, Jiaming Mei,* Peter J. Sadler,* Yangzhong Liu*. -Synuclein as a Target for Metallo-Anti-Neurodegenerative Agents. Angew. Chem. Int. Ed., 2023, 62(1), e202215360

  3. Siming Yuan, Yang Zhu, Yi Dai, Yu Wang, Duo Jin, Manman Liu, Liqin Tang,* Fabio Arnesano, Giovanni Natile,* Yangzhong Liu*. 19F NMR Allows to Investigate the Fate of Platinum(IV) Prodrugs in Physiological Conditions, Angew. Chem. Int. Ed., 2022, 61(4) e202114250

  4. Yang Zhu,# Wenyu Wang,# Junjie Cheng,# Chao Zhao, Yi Dai, Manman Liu, Jianing Yu, Chengming Wang, Huijuan Wang, Sicong Wang, Yunteng Qu, Yuen Wu*, Yangzhong Liu*. Stimuli-Responsive Manganese Single-Atom Nanozyme for Tumor Therapy via Integrated Cascade Reactions, Angew. Chem. Int. Ed., 2021, 60(17), 9480-9488

  5. Tiantian Fang,# Wanbiao Chen,# Yaping Sheng, Siming Yuan, Qiaowei Tang, Gongyu Li, Guangming Huang, Jihu Su, Xuan Zhang,* Jianye Zang,* Yangzhong Liu*. Tetrathiomolybdate Induces Dimerization of the Metal-binding Domain of ATPase and Inhibits Platination of the Protein. Nat. Commun., 2019, 10, 186